[Clinical significance of intracellular cytokines in patients with yersiniosis].

ABSTRACT

AIM: To evaluate clinical value of intracellular content of interferon-gamma (If-g), IL-2 and IL-4 in different forms of yersiniosis. MATERIAL AND METHODS: The number of If-g, IL-2 and IL-4 producing cells was estimated in 35 patients with generalized (n = 21, group 1) and secondary-focal (n = 14, group 2) forms of yersiniosis. RESULTS: The control over the number of If-g, IL-2 and IL-4 producing cells in the blood enables valid prognosis of the course and outcome of yersiniosis. CONCLUSION: Pathological processes developing in acute yersiniosis are based on interleukin-dependent immunopathology.