Violent persons with schizophrenia and comorbid disorders: a functional magnetic resonance imaging study.
Schizophr Res
; 91(1-3): 97-102, 2007 Mar.
Article
em En
| MEDLINE
| ID: mdl-17291724
ABSTRACT
The main goal of this functional Magnetic Resonance Imaging (fMRI) study was to verify the hypothesis that seriously violent persons with Sz and the co-morbid diagnoses of an Antisocial Personality Disorder (APD) and a Substance Use Disorder (Sz+APD+SUD) would present a different pattern of prefrontal functioning than seriously violent persons with Sz only. In support with the main hypothesis, frontal basal cortices were significantly less activated in persons with Sz+APD+SUD during the execution of a go/no-go task than in persons with Sz only and non-violent persons without a mental illness. In contrast, significantly higher activations in frontal motor, premotor and anterior cingulate regions were observed in the Sz+APD+SUD group than in the Sz-only group.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Esquizofrenia
/
Violência
/
Encéfalo
/
Imageamento por Ressonância Magnética
/
Transtornos Relacionados ao Uso de Substâncias
/
Transtorno da Personalidade Antissocial
Tipo de estudo:
Diagnostic_studies
Limite:
Adult
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
Schizophr Res
Assunto da revista:
PSIQUIATRIA
Ano de publicação:
2007
Tipo de documento:
Article
País de afiliação:
Finlândia