[Does cataract surgery increase the risk of exudative age-related macular degeneration? Results from a large retrospective case-control study]. / Besteht ein Zusammenhang zwischen einer Kataraktoperation und nachfolgender exsudativer altersbedingter Makuladegeneration? Eine grosse retrospektive Fallkontrollstudie.
Klin Monbl Augenheilkd
; 224(4): 288-91, 2007 Apr.
Article
em De
| MEDLINE
| ID: mdl-17458794
ABSTRACT
BACKGROUND:
Many epidemiological studies indicate a positive correlation between cataract surgery and the subsequent progression of age-related macular degeneration (AMD). Such a correlation would have far-reaching consequences. However, in epidemiological studies it is difficult to determine the significance of a single risk factor, such as cataract surgery. PATIENTS ANDMETHODS:
We performed a retrospective case-control study of patients with new onset exudative age-related macular degeneration to determine if cataract surgery was a predisposing factor. A total of 1496 eyes were included in the study 984 cases with new onset of exudative AMD and 512 control eyes with early signs of age-related maculopathy. Lens status (phakic or pseudophakic) was determined for each eye.RESULTS:
There was no significant difference in lens status between study and control group (227/984 [23.1 %] vs. 112/512 [21.8 %] pseudophakic, p = 0.6487; OR = 1.071; 95 % CI = 0.8284-1.384). In cases with bilateral pseudophakia (n = 64) no statistically significant difference of the interval between cataract surgery in either eye and the onset of exudative AMD in the study eye was found (225.9 +/- 170.4 vs. 209.9 +/- 158.2 weeks, p = 0.27).CONCLUSIONS:
Our results provide evidence that cataract surgery is not a major risk factor for the development of exudative AMD.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Extração de Catarata
/
Medição de Risco
/
Degeneração Macular
Tipo de estudo:
Diagnostic_studies
/
Etiology_studies
/
Incidence_studies
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Limite:
Female
/
Humans
/
Male
País/Região como assunto:
Europa
Idioma:
De
Revista:
Klin Monbl Augenheilkd
Ano de publicação:
2007
Tipo de documento:
Article