[Surgical strategy for malignant glioma resection with intraoperative use of fluorescein Na].
No Shinkei Geka
; 35(6): 557-62, 2007 Jun.
Article
em Ja
| MEDLINE
| ID: mdl-17564048
ABSTRACT
Cytoreductive surgery is accepted by many neurosurgeons to be the best treatment for patients with malignant gliomas. Resection of a contrast-enhancing lesion on a CT or MR image is a particularly common treatment, because observation of such lesions indicates the presence of viable tumor cells. We have used intravenous injection of fluorescein Na (0.2 cc/kg body weight) as a chemical probe for resection of malignant gliomas. Following this injection, the yellow-stained tumor is visible to the naked eye. For tumors located in an eloquent area, resection is performed at the surface of the yellow-stained tumor, or tumor debulking within the yellow-colored lesion is conducted until the resection surface becomes pale yellow. For tumors located in non-eloquent regions, suction of peritumoral white matter is also required. This procedure requires no special equipment and has wide applicability in resection of malignant gliomas.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Neoplasias Encefálicas
/
Monitorização Intraoperatória
/
Fluoresceína
/
Corantes Fluorescentes
/
Glioma
Tipo de estudo:
Diagnostic_studies
Limite:
Humans
Idioma:
Ja
Revista:
No Shinkei Geka
Ano de publicação:
2007
Tipo de documento:
Article
País de afiliação:
Japão