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[Surgical strategy for malignant glioma resection with intraoperative use of fluorescein Na].
Uzuka, Takeo; Takahashi, Hideaki; Fuji, Yukihiko.
Afiliação
  • Uzuka T; Department of Neurosurgery, Brain Research Institute, University of Niigata, 757 Asahimachi-dori-1, Niigata City, Niigata 951-8585, Japan.
No Shinkei Geka ; 35(6): 557-62, 2007 Jun.
Article em Ja | MEDLINE | ID: mdl-17564048
ABSTRACT
Cytoreductive surgery is accepted by many neurosurgeons to be the best treatment for patients with malignant gliomas. Resection of a contrast-enhancing lesion on a CT or MR image is a particularly common treatment, because observation of such lesions indicates the presence of viable tumor cells. We have used intravenous injection of fluorescein Na (0.2 cc/kg body weight) as a chemical probe for resection of malignant gliomas. Following this injection, the yellow-stained tumor is visible to the naked eye. For tumors located in an eloquent area, resection is performed at the surface of the yellow-stained tumor, or tumor debulking within the yellow-colored lesion is conducted until the resection surface becomes pale yellow. For tumors located in non-eloquent regions, suction of peritumoral white matter is also required. This procedure requires no special equipment and has wide applicability in resection of malignant gliomas.
Assuntos
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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Encefálicas / Monitorização Intraoperatória / Fluoresceína / Corantes Fluorescentes / Glioma Tipo de estudo: Diagnostic_studies Limite: Humans Idioma: Ja Revista: No Shinkei Geka Ano de publicação: 2007 Tipo de documento: Article País de afiliação: Japão
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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Encefálicas / Monitorização Intraoperatória / Fluoresceína / Corantes Fluorescentes / Glioma Tipo de estudo: Diagnostic_studies Limite: Humans Idioma: Ja Revista: No Shinkei Geka Ano de publicação: 2007 Tipo de documento: Article País de afiliação: Japão