Identification of a new mutation in Escherichia coli that suppresses a pbpB (Ts) phenotype in the presence of penicillin-binding protein 1B.
FEMS Microbiol Lett
; 68(1): 7-13, 1991 Nov 01.
Article
em En
| MEDLINE
| ID: mdl-1769557
ABSTRACT
Analysis of the functional role of penicillin-binding protein 1B (PBP1B) of Escherichia coli led us to find a new mutation able to suppress thermosensitive growth of the pbpB2158(Ts) mutant strain, which harbors a thermosensitive PBP3 protein only in the presence of a ponB+ background. The mutation, originally isolated in a strain with a high dosage of PBP1B, could also suppress the pbpB(Ts) phenotype when a single copy of the ponB gene was introduced. These results clearly give further support to the implication of PPB1B in the septation process in Escherichia coli.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Penicilinas
/
Supressão Genética
/
Proteínas de Bactérias
/
Muramilpentapeptídeo Carboxipeptidase
/
Proteínas de Transporte
/
Peptidil Transferases
/
Proteínas de Escherichia coli
/
D-Ala-D-Ala Carboxipeptidase Tipo Serina
/
Peptidoglicano Glicosiltransferase
/
Escherichia coli
Tipo de estudo:
Diagnostic_studies
Idioma:
En
Revista:
FEMS Microbiol Lett
Ano de publicação:
1991
Tipo de documento:
Article
País de afiliação:
Espanha