Lead exposure induces pycnosis and enucleation of peripheral erythrocytes in the domestic fowl.
Vet J
; 178(1): 109-14, 2008 Oct.
Article
em En
| MEDLINE
| ID: mdl-17719252
ABSTRACT
Lead (Pb) shot were administered orally to young chickens to determine the effects on red blood cells (RBCs). The concentrations of Pb in the blood of young chickens rose rapidly after Pb administration and were maintained at high levels for several days. The number of RBCs with pycnotic nuclei, reticulocytes and enucleated RBCs increased concurrently. Pycnotic nuclei were surrounded by enlarged nucleolemmal cisternae, which sometimes opened to the extracellular space. Gel electrophoresis showed that the presence of pycnotic nuclei was not associated with DNA fragmentation typical of apoptosis. It was concluded that exposure to lead shot changes nuclear morphology in the peripheral blood of domestic fowl.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Doenças das Aves Domésticas
/
Galinhas
/
Eritrócitos
/
Chumbo
/
Intoxicação por Chumbo
Limite:
Animals
Idioma:
En
Revista:
Vet J
Assunto da revista:
MEDICINA VETERINARIA
Ano de publicação:
2008
Tipo de documento:
Article
País de afiliação:
Japão