The osteoclast-not always guilty.
Cell Metab
; 6(3): 157-9, 2007 Sep.
Article
em En
| MEDLINE
| ID: mdl-17767902
ABSTRACT
Osteopetrosis is usually regarded as the disease of nonfunctioning osteoclasts, with a consequent accumulation of osseocartilaginous material in the bone marrow. A recent report shows that, in some patients with the rare autosomal recessive form of the disease, the osteoclast defect may be non-cell autonomous, in this case due to a mutation in RANKL, the protein that normally controls osteoclast formation and activity.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Osteoclastos
/
Osteopetrose
Limite:
Humans
Idioma:
En
Revista:
Cell Metab
Assunto da revista:
METABOLISMO
Ano de publicação:
2007
Tipo de documento:
Article
País de afiliação:
Estados Unidos