Lipophilic sugar nucleotide synthesis by structure-based design of nucleotidylyltransferase substrates.
Org Biomol Chem
; 6(3): 477-84, 2008 Feb 07.
Article
em En
| MEDLINE
| ID: mdl-18219417
ABSTRACT
Structure-based design of alkyl sugar-1-phosphates provides an efficient nucleotidylyltransferase-catalyzed synthesis of a series of new lipophilic sugar nucleotides possessing long or branched alkyl chains, thereby demonstrating the utility of nucleotidylyltransferases to catalyze the synthesis of sugar nucleotides with potential applications in lipopolysaccharide and lipoglycopeptide biosynthesis.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Pseudomonas aeruginosa
/
Nucleotídeos
/
Nucleotidiltransferases
Idioma:
En
Revista:
Org Biomol Chem
Assunto da revista:
BIOQUIMICA
/
QUIMICA
Ano de publicação:
2008
Tipo de documento:
Article