Progressive renal disease despite immunosuppressive therapy in a patient with Wegener s granulomatosis.
Neth J Med
; 66(3): 125-7, 2008 Mar.
Article
em En
| MEDLINE
| ID: mdl-18349469
ABSTRACT
We present a patient with Morbus Wegener and crescentic glomerulonephritis. Treatment with cyclophosphamide and prednisolone resulted in the disappearance of signs and symptoms of systemic inflammation. However, renal function deteriorated. Renal biopsy showed evidence of continuing capillary necrosis. Renal function improved with added plasmapheresis treatment. This case report illustrates that in patients with vasculitis necrotizing glomerulonephritis may remain active despite immunosuppressive therapy, even in the absence of extrarenal disease activity.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Granulomatose com Poliangiite
/
Imunossupressores
/
Nefropatias
Limite:
Aged
/
Humans
/
Male
Idioma:
En
Revista:
Neth J Med
Ano de publicação:
2008
Tipo de documento:
Article
País de afiliação:
Holanda