Cardiac resynchronization therapy: can we make our heart failure patients smarter?
Trans Am Clin Climatol Assoc
; 118: 153-64, 2007.
Article
em En
| MEDLINE
| ID: mdl-18528499
ABSTRACT
Patients with congestive heart failure have impaired cognitive function, possibly caused by impaired global and regional cerebral blood flow. We hypothesized that biventricular pacing-simultaneous activation of the both the septum and the lateral wall of the left ventricle-would improve neurocognitive function and improve quality of life. Ten patients were examined before and after pacemaker implantation with standard measures of neurocognitive function. There were significant improvements in neurocognitive measures of attention (Digit Span 50 +/- 5 vs. 57 +/- 7, p = 0.04) and information processing (Symbol Digit 39 +/- 9 vs. 49 +/- 15, p = 0.04). There were also improvements in two psychosocial measure of quality of life Left Ventricular Dysfunction-36 (13 +/- 7 vs. 7 +/- 5, p = 0.004) and Minnesota Living with Heart Failure Questionnaire (49 +/- 25 vs. 23 +/- 14, p = 0.02). These results translate into clinically significant functional benefits. We conclude that biventricular pacing improves cognitive and psychosocial outcomes, specifically in the domains of attention and speed of information processing.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Estimulação Cardíaca Artificial
/
Insuficiência Cardíaca
Tipo de estudo:
Qualitative_research
Limite:
Adult
/
Aged
/
Female
/
Humans
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Male
/
Middle aged
Idioma:
En
Revista:
Trans Am Clin Climatol Assoc
Ano de publicação:
2007
Tipo de documento:
Article
País de afiliação:
Estados Unidos