Treatment of idiopathic sclerosing inflammation of the orbit (myositis) with infliximab.

ABSTRACT

PURPOSE: We report the successful use of infliximab in a young patient with idiopathic sclerosing orbital inflammation (myositis). METHODS: We describe the patient's medical records and review the literature. RESULTS: Idiopathic myositis in this patient could not be satisfactorily treated with corticosteroids or chemotherapy. Biopsy showed sclerosing orbital inflammation. The patient had a prompt and sustained response with infliximab and methotrexate treatment. CONCLUSIONS: Infliximab and methotrexate might be considered in patients with idiopathic sclerosing orbital inflammation (myositis).