[Molecular medicine in thyroid surgery]. / Medicina molecolare in chirurgia della tiroide.
Chir Ital
; 60(2): 165-78, 2008.
Article
em It
| MEDLINE
| ID: mdl-18689164
ABSTRACT
Cancer originates from a single cell which, through the acquisition of mutations in genes for key growth and survival factors, undergoes clonal expansion. Study of the genome allowed the detection of genes whose mutation is involved in tumour formation. In detail, in most thyroid neoplasms we are now able to identify the genes which cause cancer initiation. Moreover, correlations between mutations and clinico-pathological features of the tumours have been revealed. Thus, the genetic study of tumours is not anymore only a scientific curiosity, but a useful tool for the formulation of the more efficacious therapeutic and follow-up strategies. In this review we will summarize the more recent molecular medicine acquisitions in the thyroid cancer field and will describe their present and eventually future impact on the activity of the endocrine surgeon.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Neoplasias da Glândula Tireoide
Tipo de estudo:
Prognostic_studies
Limite:
Humans
Idioma:
It
Revista:
Chir Ital
Ano de publicação:
2008
Tipo de documento:
Article