The impact of histopathologic diagnosis on the proper management of testis neoplasms.
Nat Clin Pract Oncol
; 5(10): 619-22, 2008 Oct.
Article
em En
| MEDLINE
| ID: mdl-18725922
ABSTRACT
BACKGROUND:
A 45-year-old man underwent a right orchiectomy for a rapidly growing testicular mass. After histologic and imaging examinations the patient was diagnosed with stage I (T1N0M0) seminoma. Approximately 2 months after surgery the patient began to complain of abdominal pain and a CT scan revealed a bulky retroperitoneal mass. The patient did not receive the planned prophylactic radiotherapy and was treated with combined cisplatin, etoposide and bleomycin chemotherapy; after the completion of this treatment he achieved complete remission. Three years later, and while still undergoing follow-up, the patient developed multiple neurological motor deficits. INVESTIGATIONS Brain MRI and CT-guided biopsy. DIAGNOSIS Diffuse large B-cell lymphoma of the testis, relapsing in the central nervous system. MANAGEMENT High-dose methotrexate alone or in combination with high-dose cytarabine.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Neoplasias Testiculares
/
Protocolos de Quimioterapia Combinada Antineoplásica
/
Linfoma Difuso de Grandes Células B
/
Seminoma
Tipo de estudo:
Diagnostic_studies
Limite:
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
Nat Clin Pract Oncol
Assunto da revista:
NEOPLASIAS
Ano de publicação:
2008
Tipo de documento:
Article
País de afiliação:
Suíça