Rheumatoid leptomeningitis: rare complication of rheumatoid arthritis.
Clin Rheumatol
; 28(9): 1117-9, 2009 Sep.
Article
em En
| MEDLINE
| ID: mdl-19415375
ABSTRACT
Rheumatoid leptomeningitis is a rare complication of rheumatoid arthritis (RA). We describe a woman with rheumatoid leptomeningitis presenting with acute-onset behavioral changes and consciousness disturbance in the early stage of RA. On fluid-attenuated inversion recovery images or diffusion-weighted images, high-signal-intensity lesions in the subarachnoid spaces of the right frontal lobe were observed. Biopsies of brain tissues and the dura mater located in the right frontal lobe were obtained. On the basis of the findings of histopathological analysis, a diagnosis of necrotizing granulomas involving the leptomeninges consistent with rheumatoid leptomeningitis was made. An early diagnosis of rheumatoid leptomeningitis and immediate initiation of treatment may prevent neurological sequelae.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Artrite Reumatoide
/
Meningite
/
Meninges
Tipo de estudo:
Etiology_studies
/
Screening_studies
Limite:
Aged
/
Female
/
Humans
Idioma:
En
Revista:
Clin Rheumatol
Ano de publicação:
2009
Tipo de documento:
Article
País de afiliação:
Japão