[Severe bronchial spasm crises induced by topical administration of eyedrops with timolol base, a non-selective beta blocking agent]. / Gravi crisi broncospastiche indotte da applicazione topica di gocce oculari a base di timololo, un beta bloccante non selettivo.
Recenti Prog Med
; 82(7-8): 402-4, 1991.
Article
em It
| MEDLINE
| ID: mdl-1947406
ABSTRACT
Since their introduction in clinical practice beta-blocker drugs are known to be able to induce bronchospasm. However, this adverse effect may develop only in subjects with asthma, chronic bronchitis and/or airways hyper-reactivity. Although this potentially adverse effect of beta-blockers on the airways has long been recognized, its mechanism in inducing bronchospasm remains unclear. The Authors report a case of severe bronchoconstrictive episodes with respiratory failure following the administration of a timolol ophthalmic solution in a 51 yr old woman. Pharmacokinetics, preventive and therapeutic aspects of timolol eyedrop-induced bronchospasm are discussed.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Soluções Oftálmicas
/
Timolol
/
Espasmo Brônquico
Limite:
Female
/
Humans
/
Middle aged
Idioma:
It
Revista:
Recenti Prog Med
Ano de publicação:
1991
Tipo de documento:
Article