Globulixanthone F, a new polyoxygenated xanthone with an isoprenoid group and two antimicrobial biflavonoids from the stem bark of Symphonia globulifera.
Nat Prod Commun
; 4(6): 803-8, 2009 Jun.
Article
em En
| MEDLINE
| ID: mdl-19634326
ABSTRACT
Bioassay-guided fractionation of the stem bark of Symphonia globulifera has yielded three known xanthones, ugaxanthone (1), mbarraxanthone (2) and gentisein (3), two biflavonoid derivatives named GB2 (4) and manniflavanone GB3 (5), and one new polyoxygenated xanthone with an isoprenoid group, named globulixanthone F (6). The structures of these compounds were elucidated by means of spectroscopic methods. The spectral data of 1 and 2 are reported here for the first time, as well as the antimicrobial activity of globulixanthone F against a range of microorganisms. We also report the total synthesis of the xanthone skeleton.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Flavonoides
/
Clusiaceae
/
Casca de Planta
/
Xantonas
/
Anti-Infecciosos
Idioma:
En
Revista:
Nat Prod Commun
Assunto da revista:
BOTANICA
/
FARMACOLOGIA
/
QUIMICA
Ano de publicação:
2009
Tipo de documento:
Article
País de afiliação:
Camarões