sTNFR-1 is an early inflammatory marker in community versus institutionalized elderly women.
Inflamm Res
; 59(2): 129-34, 2010 Feb.
Article
em En
| MEDLINE
| ID: mdl-19701605
ABSTRACT
OBJECTIVE AND DESIGN:
To evaluate plasma sTNFR-1 and IL-6 levels and correlate with hand grip in the institutionalized and community living Brazilian elderly.MATERIAL:
A convenience sample of 110 elderly women (71.17 + or - 7.44 years) was selected. Plasma sTNFR-1 and IL-6 levels were measured by ELISA. For the measurement of hand grip, a JAMAR dynamometer was used.RESULTS:
Plasma concentrations of inflammatory markers were significantly higher in institutionalized elderly (sTNFR-1 479 + or - 22 pg/mL; IL-6 6.3 + or - 0.8 pg/mL) than in community-dwelling elderly (sTNFR-1 329 + or - 24 pg/mL; IL-6 2.5 + or - 0.4 pg/mL; P < 0.0001). Institutionalized elderly had reduced hand grip (15 + or - 0.8 Kgf) in comparison to community dwelling elderly (23 + or - 0.6 Kgf; P < 0.05). When individuals were subdivided in age groups, sTNFR-1 was higher in community dwelling versus institutionalized elderly in the 60-70 age range.CONCLUSIONS:
Our results demonstrate that being institutionalized has an impact on levels of inflammatory markers.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Características de Residência
/
Receptores Tipo I de Fatores de Necrose Tumoral
/
Inflamação
/
Institucionalização
Tipo de estudo:
Observational_studies
/
Prevalence_studies
/
Risk_factors_studies
Limite:
Aged
/
Aged80
/
Female
/
Humans
/
Middle aged
País/Região como assunto:
America do sul
/
Brasil
Idioma:
En
Revista:
Inflamm Res
Assunto da revista:
ALERGIA E IMUNOLOGIA
/
PATOLOGIA
Ano de publicação:
2010
Tipo de documento:
Article
País de afiliação:
Brasil