[Medication associated long QT syndrome]. / Medikamenten-assoziiertes Long-QT-Syndrom.
Praxis (Bern 1994)
; 98(24): 1409-15; quiz 1415, 2009 Dec 02.
Article
em De
| MEDLINE
| ID: mdl-19953465
ABSTRACT
We report on a 76 year old woman who fainted on her way to the restroom during the night. At the emergency department, a prolonged QT-interval was noticed in addition to sinusbradycardia and marginal hypokalemia. The QT-interval normalized promptly after citalopram was discontinued. Taking into account the clinical picture and the ascertained orthostatic dysregulation, a diagnosis of orthostatic syncope was made. Because of the lengthened QT-interval, drug-induced torsade de pointes ventricular arrhythmia was considered as a differential diagnosis. We describe that citalopram was most probably the cause for the prolonged QT-interval. In our article we discuss the pathophysiology of drug-induced long QT syndrome (LQTS), the most important drugs involved, and finally the prophylaxis and treatment of a TdP ventricular arrhythmia.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Esquizofrenia Paranoide
/
Antipsicóticos
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Benzodiazepinas
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Síndrome do QT Longo
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Citalopram
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Antidepressivos de Segunda Geração
/
Transtorno Depressivo
Tipo de estudo:
Diagnostic_studies
/
Risk_factors_studies
Limite:
Aged
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Female
/
Humans
Idioma:
De
Revista:
Praxis (Bern 1994)
Assunto da revista:
MEDICINA
Ano de publicação:
2009
Tipo de documento:
Article