[Obstetric complications and early-onset schizophrenia: a case-control study]. / Complicanze ostetriche e schizofrenia a esordio precoce: uno studio caso-controllo.
Riv Psichiatr
; 44(2): 117-21, 2009.
Article
em It
| MEDLINE
| ID: mdl-20066813
AIM: Research has suggested an association between obstetric complications and schizophrenia. METHODS: In this study data based on the obstetric birth case-notes of adolescent patients with diagnosed schizophrenia were compared to those of normal "healthy" same-aged control subjects. RESULTS: Complications involving a clear damaging potential (Level > 4 in the McNeil-Sjöström Scale) were seen significantly more often among cases than control subjects: 7% vs 2%, Fisher's exact test p < 0.04, odds ratio 4, 95%, CI: 1.048-15.26. DISCUSSION: Brain-damaging due to obstetric complications would seem to be a possible antecedent to a diagnosis of schizophrenia. Moreover, results support the evidence that obstetric adversity exerts an independent influence on the age at first presentation with schizophrenia. This finding suggests the existence of a causal relationship between obstetric adversity and age at onset of schizophrenia even if the small samples size limits the power of this study.
Buscar no Google
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Complicações na Gravidez
/
Esquizofrenia
Tipo de estudo:
Observational_studies
/
Risk_factors_studies
Limite:
Adolescent
/
Child
/
Female
/
Humans
/
Male
/
Pregnancy
Idioma:
It
Revista:
Riv Psichiatr
Ano de publicação:
2009
Tipo de documento:
Article