Analysis of perchlorate in milk powder and milk by hydrophilic interaction chromatography combined with tandem mass spectrometry.
J Agric Food Chem
; 58(6): 3736-40, 2010 Mar 24.
Article
em En
| MEDLINE
| ID: mdl-20170169
ABSTRACT
A simple, selective, and sensitive method using hydrophilic interaction chromatography combined with tandem mass spectrometry (HILIC-MS/MS) for quantifying perchlorate in milk powder and milk was developed. The analysis was conducted on an Inertsil HILIC column (150 mm x 3.0 mm, 3.5 mum) using a mobile phase consisting of methanol and 0.1% formic acid (6040, v/v). The detection was performed by MS/MS via electrospray ionization. Linear calibration curves were obtained in the concentration range of 2.00 x 10(-2) to 8.00 microg/g and 4.00 x 10(-1) to 20.0 microg/L for perchlorate in milk powder and milk, respectively. The method detection limit was 4.00 x 10(-3) microg/g for milk powder and 8.00 x 10(-2) microg/L for milk. The recoveries of perchlorate in milk powder and milk were all >90%. This method was successfully applied to the quantitative determination of perchlorate in milk powder and milk.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Cromatografia
/
Percloratos
/
Leite
/
Espectrometria de Massas em Tandem
Tipo de estudo:
Evaluation_studies
Limite:
Animals
Idioma:
En
Revista:
J Agric Food Chem
Ano de publicação:
2010
Tipo de documento:
Article