A chromosomal translocation causing overproduction of iso-2-cytochrome c in yeast.
Genetics
; 88(4 Pt 1): 689-707, 1978 Apr.
Article
em En
| MEDLINE
| ID: mdl-206486
ABSTRACT
The CYC7-1 mutation in the yeast Saccharomyces cerevisiae causes the production of approximately 30 times the normal amount of iso-2-cytochrome c. Genetic analysis established that the CYC7-1 mutation is a reciprocal translocation involving the left arm of chromosome V and the right arm of chromosome XVI. The chromosome V arm was broken adjacent to the gene CYC7, which determines the primary structure of iso-2-cytochrome c, and this fragment containing the CYC7 gene was joined to the segment of chromosome XVI. It appears as though the elevation of iso-2-cytochrome c is caused by an abnormal controlling region adjacent to the structural region of the CYC7 gene.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Translocação Genética
/
Genes Reguladores
/
Grupo dos Citocromos c
Idioma:
En
Revista:
Genetics
Ano de publicação:
1978
Tipo de documento:
Article