Fabrication of a microfluidic Ag/AgCl reference electrode and its application for portable and disposable electrochemical microchips.
Electrophoresis
; 31(18): 3083-9, 2010 Sep.
Article
em En
| MEDLINE
| ID: mdl-20803753
ABSTRACT
This report describes a convenient method for the fabrication of a miniaturized, reliable Ag/AgCl reference electrode with nanofluidic channels acting as a salt bridge that can be easily integrated into microfluidic chips. The Ag/AgCl reference electrode shows high stability with millivolt variations. We demonstrated the application of this reference electrode in a portable microfluidic chip that is connected to a USB-port microelectrochemical station and to a computer for data collection and analysis. The low fabrication cost of the chip with the potential for mass production makes it disposable and an excellent candidate for real-world analysis and measurement. We used the chip to quantitatively analyze the concentrations of heavy metal ions (Cd(2+) and Pb(2+)) in sea water. We believe that the Ag/AgCl reference microelectrode and the portable electrochemical system will be of interest to people in microfluidics, environmental science, clinical diagnostics, and food research.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Prata
/
Compostos de Prata
/
Eletroforese Capilar
/
Técnicas Analíticas Microfluídicas
Idioma:
En
Revista:
Electrophoresis
Ano de publicação:
2010
Tipo de documento:
Article