Gold(I)-catalyzed cyclization of ß-allenylhydrazones: an efficient synthesis of multisubstituted N-aminopyrroles.
Org Lett
; 12(19): 4396-9, 2010 Oct 01.
Article
em En
| MEDLINE
| ID: mdl-20825210
ABSTRACT
The gold(I)-catalyzed cycloisomerization of ß-allenylhydrazones provides an efficient access to multisubstituted N-aminopyrroles, which are obtained in good to excellent yields. This new intramolecular cyclization method can be applied either to alkyl- or aryl-substituted allenes. The reaction proceeds under mild conditions with short reaction times through a selective intramolecular 1,2-alkyl or -aryl migration extending the general scope of the reaction.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Idioma:
En
Revista:
Org Lett
Assunto da revista:
BIOQUIMICA
Ano de publicação:
2010
Tipo de documento:
Article
País de afiliação:
França