Umbilical cord blood stem cells - potential therapeutic tool for neural injuries and disorders.
Acta Neurobiol Exp (Wars)
; 70(3): 316-24, 2010.
Article
em En
| MEDLINE
| ID: mdl-20871652
ABSTRACT
Brain limited self-renewal capability is the main element behind the seriousness of neurodegenerative diseases and neural injuries. Any possible attempts to use cell replacement-therapy approaches rely on first, the ability of such cells to generate neural cells and tissues with developmental and functional similarities to human brain cells and second, development of safe and effective protocols for cells transplantations. Many recent studies showed that human umbilical cord blood stem cells have the potential to generate cells with neuronal characteristics. It has also been shown that these stem cells have a positive impact on animal models of neural injuries and diseases. Umbilical cord blood stem cells are a potential candidate for clinical therapies for neural injuries and neural degenerative diseases for which current mode of therapy is inadequate. In addition, they might provide an in-vitro model of parenchymal neural cells for toxicology and drugs testing research.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Células-Tronco
/
Traumatismos do Sistema Nervoso
/
Transplante de Células-Tronco de Sangue do Cordão Umbilical
/
Sangue Fetal
/
Doenças do Sistema Nervoso
Tipo de estudo:
Guideline
/
Prognostic_studies
Limite:
Humans
Idioma:
En
Revista:
Acta Neurobiol Exp (Wars)
Ano de publicação:
2010
Tipo de documento:
Article
País de afiliação:
Reino Unido