[A retrospective efficacy and safety study of UVB-TL01 phototherapy and PUVA therapy in palmoplantar psoriasis]. / Étude rétrospective de l'efficacité et de la tolérance de la photothérapie UVBTL01 et de la PUVAthérapie dans le psoriasis palmoplantaire.
Ann Dermatol Venereol
; 137(10): 597-603, 2010 Oct.
Article
em Fr
| MEDLINE
| ID: mdl-20932438
ABSTRACT
BACKGROUND:
Topical therapy is generally insufficient in palmoplantar psoriasis. UVBTL01 phototherapy is a therapeutic alternative and we conducted a retrospective study of the efficacy and safety of this approach and of PUVA therapy in palmoplantar psoriasis. PATIENTS ANDMETHODS:
All patients treated with UVBTL01 or PUVA therapy from November 2001 to April 2008 were included in the study. Phototherapy was given three times a week. Evaluation was performed after 20 sessions, again after 30 sessions and then at the end of the treatment. Therapeutic outcome was classed as "failure", "slight improvement" or "improvement or clear skin".RESULTS:
UVBTL01 phototherapy and PUVA therapy were effective, with "improvement or clear skin" in respectively 52% and 61% of cases and "slight improvement" in 16% and 23% of cases at the end of the treatment. With UVBTL01, adverse effects occurred in 20% of cases (erythema 18%, first-degree burns 7%) and treatment was discontinued as a result in only 4% of cases. Adverse effects occurred in 50% in patients on PUVA therapy, mainly due to methoxypsoralen intake.CONCLUSION:
UVBTL01 phototherapy and PUVA therapy are efficacious treatments in palmoplantar psoriasis; UVBTL01 phototherapy involves fewer constraints and has fewer adverse effects.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Psoríase
/
Terapia PUVA
/
Terapia Ultravioleta
/
Dermatoses do Pé
/
Dermatoses da Mão
Tipo de estudo:
Diagnostic_studies
/
Observational_studies
Limite:
Adult
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
Fr
Revista:
Ann Dermatol Venereol
Ano de publicação:
2010
Tipo de documento:
Article
País de afiliação:
França