Asymmetric synthesis and biological activity of nor-α-tocopherol, a new vitamin E analogue.
Chembiochem
; 12(1): 118-24, 2011 Jan 03.
Article
em En
| MEDLINE
| ID: mdl-21161968
ABSTRACT
The vitamin E analogues (2R,4'R,8'R)-nor-α-tocopherol (94 % de) and (2RS,4'R,8'R)-nor-α-tocopherol have been synthesized from (all R)-hexahydrofarnesol and phytol, respectively. According to in vitro experiments with murine macrophages nor-α-tocopherol is an anti-inflammatory compound more potent than α-tocopherol.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Alfa-Tocoferol
/
Antioxidantes
Limite:
Animals
Idioma:
En
Revista:
Chembiochem
Assunto da revista:
BIOQUIMICA
Ano de publicação:
2011
Tipo de documento:
Article
País de afiliação:
Suíça