Posterior brain in fetuses with open spina bifida at 11 to 13 weeks.
Prenat Diagn
; 31(1): 103-6, 2011 Jan.
Article
em En
| MEDLINE
| ID: mdl-21188735
ABSTRACT
OBJECTIVE:
To measure the changes in the posterior fossa in first-trimester fetuses with open spina bifida (OSB).METHODS:
The brain stem diameter and brain stem to occipital bone (BSOB) diameter were measured in stored images of the mid-sagittal view of the fetal face at 11(+0) to 13(+6) weeks from 30 fetuses with OSB and 1000 normal controls.RESULTS:
In the control group, the brain stem and BSOB diameter increased significantly with crown-rump length (CRL) and the brain stem to BSOB ratio decreased. In the spina bifida group, the brain stem diameter was above the 95th percentile of the control group in 29 (96.7%) cases, the BSOB diameter was below the 5th percentile in 26 (86.7%) and the brain stem to BSOB ratio was above the 95th percentile in all cases.CONCLUSIONS:
At 11 to 13 weeks the majority of fetuses with OSB have measurable abnormalities in the posterior brain.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Encéfalo
/
Espinha Bífida Cística
/
Ultrassonografia Pré-Natal
/
Idade Gestacional
Tipo de estudo:
Diagnostic_studies
Limite:
Female
/
Humans
/
Pregnancy
Idioma:
En
Revista:
Prenat Diagn
Ano de publicação:
2011
Tipo de documento:
Article
País de afiliação:
Reino Unido