Bambino: a variant detector and alignment viewer for next-generation sequencing data in the SAM/BAM format.
Bioinformatics
; 27(6): 865-6, 2011 Mar 15.
Article
em En
| MEDLINE
| ID: mdl-21278191
ABSTRACT
SUMMARY:
Bambino is a variant detector and graphical alignment viewer for next-generation sequencing data in the SAM/BAM format, which is capable of pooling data from multiple source files. The variant detector takes advantage of SAM-specific annotations, and produces detailed output suitable for genotyping and identification of somatic mutations. The assembly viewer can display reads in the context of either a user-provided or automatically generated reference sequence, retrieve genome annotation features from a UCSC genome annotation database, display histograms of non-reference allele frequencies, and predict protein-coding changes caused by SNPs.AVAILABILITY:
Bambino is written in platform-independent Java and available from https//cgwb.nci.nih.gov/goldenPath/bamview/documentation/index.html, along with documentation and example data. Bambino may be launched online via Java Web Start or downloaded and run locally.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Gráficos por Computador
/
Software
/
Análise Mutacional de DNA
/
Alinhamento de Sequência
Idioma:
En
Revista:
Bioinformatics
Assunto da revista:
INFORMATICA MEDICA
Ano de publicação:
2011
Tipo de documento:
Article
País de afiliação:
Estados Unidos