First total synthesis of papilistatin.

Wu, Meng; Li, Ling; Feng, An-Zheng; Su, Bo; Liang, De-min; Liu, Yu-xiu; Wang, Qing-min

Wu, Meng; Li, Ling; Feng, An-Zheng; Su, Bo; Liang, De-min; Liu, Yu-xiu; Wang, Qing-min.

Afiliação

Wu M; State Key Laboratory of Elemento-Organic Chemistry, Research Institute of Elemento-Organic Chemistry, Nankai University, Tianjin 300071, People's Republic of China.

Org Biomol Chem ; 9(7): 2539-42, 2011 Apr 07.

Article em En | MEDLINE | ID: mdl-21344073

ABSTRACT

ABSTRACT

Papilistatin has been isolated recently and found to have good anticancer and antibacterial activity. Papilistatin is a unique phenanthrene-1,10-dicarboxylic acid. The first total synthesis of papilistatin is described here with radical cyclisation as the key step.

Assuntos

Dioxóis/síntese química; Fenantrenos/síntese química; Estrutura Molecular

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fenantrenos / Dioxóis Idioma: En Revista: Org Biomol Chem Assunto da revista: BIOQUIMICA / QUIMICA Ano de publicação: 2011 Tipo de documento: Article

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