Can the use of hyaluronidase reduce capsule formation?
Aesthetic Plast Surg
; 35(5): 782-8, 2011 Oct.
Article
em En
| MEDLINE
| ID: mdl-21424174
ABSTRACT
BACKGROUND:
The purpose of this study was to find whether the use of hyaluronidase reduces capsule formation.METHODS:
Ten New Zealand White rabbits were used. Eight pockets were created using an aseptic technique, four on the right side and four on the left side, along the vertebral column of every animal. One piece of silicone from a silicone block was inserted inside every pocket. The dimensions of each piece were 3.5 × 2 × 1.5 cm. In every pocket on the right side of each animal we placed 0.5 ml of hyaluronidase solution. The animals were sacrificed 5 months postoperatively. Capsule formation in the each side of the animals was compared.RESULTS:
Two rabbits presented infection in two pockets and were excluded from the study. There was a statistically significant difference between groups concerning the capsule thickness variable using parametric (P = 0.003) and nonparametric (P = 0.001) analysis [capsule thickness on the right side 256.46 ± 114.88 (mean ± SD) and on the left side 369.10 ± 147.81 (mean ± SD); capsule thickness on the right side 235.69 (104.72) [median (IQR)] and on the left side 332.12 (188.68) median (IQR)].CONCLUSION:
The use of hyaluronidase may reduce capsule formation around implants.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Silicones
/
Cicatrização
/
Falha de Prótese
/
Implantes de Mama
/
Implante Mamário
/
Hialuronoglucosaminidase
Tipo de estudo:
Etiology_studies
/
Prognostic_studies
Limite:
Animals
Idioma:
En
Revista:
Aesthetic Plast Surg
Ano de publicação:
2011
Tipo de documento:
Article
País de afiliação:
Grécia