In Vitro and in Vivo Characteristics of Fluorapatite-Forming Calcium Phosphate Cements.
J Res Natl Inst Stand Technol
; 115(4): 267-276, 2010.
Article
em En
| MEDLINE
| ID: mdl-21479080
ABSTRACT
This study reports for the first time in vitro and in vivo properties of fluorapatite (FA)-forming calcium phosphate cements (CPCs). The experimental cements contained from (0 to 3.1) mass % of F, corresponding to presence of FA at levels of approximately (0 to 87) mass %. The crystallinity of the apatitic cement product increased greatly with the FA content. When implanted subcutaneously in rats, the in vivo resorption rate decreased significantly with increasing FA content. The cement with the highest FA content was not resorbed in soft tissue, making it the first known biocompatible and bioinert CPC. These bioinert CPCs might be useful for applications where slow or no resorption of the implant is required to achieve the desired clinical outcome.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Idioma:
En
Revista:
J Res Natl Inst Stand Technol
Ano de publicação:
2010
Tipo de documento:
Article
País de afiliação:
Estados Unidos