Fundus autofluorescence in autosomal dominant occult macular dystrophy.
Arch Ophthalmol
; 129(5): 597-602, 2011 May.
Article
em En
| MEDLINE
| ID: mdl-21555613
ABSTRACT
OBJECTIVE:
To characterize fundus autofluorescence (FAF) images of eyes with autosomal dominant occult macular dystrophy (OMD).METHODS:
All patients received a comprehensive ophthalmologic examination for diagnosis of OMD. We evaluated the FAF images in 13 eyes of 7 patients with autosomal dominant OMD by confocal scanning laser ophthalmoscopy with excitation at 488 nm and emission more than 500 nm.RESULTS:
The FAF images showed unspecific weak foveal hyperfluorescence in 4 eyes of 2 patients; one showed a thin hyperfluorescence in the temporal fovea bilaterally and the other showed weak hyperfluorescence in the fovea bilaterally. The optical coherence tomographic images showed abnormalities of the photoreceptor inner segment-outer segment line and cone outer segment tip line in all patients. However, 5 patients had normal FAF images regardless of morphological abnormalities of the photoreceptor.CONCLUSIONS:
Fundus autofluorescence is a useful method to acquire additional information of photoreceptor/retinal pigment epithelium function in eyes with OMD. Fundus autofluorescence will be also helpful for the differential diagnosis of eyes with OMD vs eyes with other dystrophies that have a distinctive FAF pattern.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Retina
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Angiofluoresceinografia
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Genes Dominantes
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Degeneração Macular
Limite:
Aged
/
Aged80
/
Female
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Humans
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Male
/
Middle aged
Idioma:
En
Revista:
Arch Ophthalmol
Ano de publicação:
2011
Tipo de documento:
Article
País de afiliação:
Japão