PileLineGUI: a desktop environment for handling genome position files in next-generation sequencing studies.
Nucleic Acids Res
; 39(Web Server issue): W562-6, 2011 Jul.
Article
em En
| MEDLINE
| ID: mdl-21646339
ABSTRACT
Next-generation sequencing (NGS) technologies are making sequence data available on an unprecedented scale. In this context, new catalogs of Single Nucleotide Polymorphism and mutations generated by resequencing studies are usually stored in genome position files (e.g. Variant Call Format, SAMTools pileup, BED, GFF) comprising of large lists of genomic positions, which are difficult to handle by researchers. Here, we present PileLineGUI, a novel desktop application primarily designed for manipulating, browsing and analysing genome position files (GPF), with specific support to somatic mutation finding studies. The developed tool also integrates a new genome browser module specially designed for inspecting GPFs. PileLineGUI is free, multiplatform and designed to be intuitively used by biomedical researchers. PileLineGUI is available at http//sing.ei.uvigo.es/pileline/pilelinegui.html.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Software
/
Genoma
/
Análise de Sequência de DNA
/
Sequenciamento de Nucleotídeos em Larga Escala
Idioma:
En
Revista:
Nucleic Acids Res
Ano de publicação:
2011
Tipo de documento:
Article
País de afiliação:
Espanha