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Repair of ruptured abdominal aortic aneurysm in octogenarians.
Opfermann, P; von Allmen, R; Diehm, N; Widmer, M K; Schmidli, J; Dick, F.
Afiliação
  • Opfermann P; Department of Cardiovascular Surgery, Swiss Cardiovascular Centre, University Hospital Berne, Freiburgstrasse, 3010 Berne, Switzerland.
Eur J Vasc Endovasc Surg ; 42(4): 475-83, 2011 Oct.
Article em En | MEDLINE | ID: mdl-21693385
OBJECTIVE: To determine whether advanced age was independently associated with prohibitive surgical risks or impaired long-term prognosis after ruptured aortic aneurysm repair. DESIGN: Post-hoc analysis of prospective cohort. MATERIALS: Consecutive patients undergoing ruptured aneurysm repair between January 2001 and December 2010 at a tertiary referral centre. METHODS: Surgical mortality (i.e., <30 days) was compared between octogenarians and younger patients using logistic regression modelling to adjust for suspected confounders and to identify prognostic factors. Long-term survival was compared with matched national populations. RESULTS: Sixty of 248 involved patients were octogenarians (24%) and almost all were offered open repair (n = 237). Surgical mortality of octogenarians was 26.7% (adjusted odds ratio (OR) 2.1; 95% confidence interval (CI), 0.9-5.2) and confounded by cardiac disease. Hypovolaemic shock predicted perioperative death of octogenarians best (OR 5.1; 95%CI, 1.1-23.4; P = 0.037). After successful repair, annual mortality of octogenarians averaged 13.7% vs. 5.2% for younger patients. At 2 years, octogenarian survival was at 94% of the expected 'normal' survival in the general population (vs. 96% for younger patients). CONCLUSIONS: Surgical mortality of ruptured aneurysm repair was not independently related to advanced age but mainly driven by cardiac disease and manifest hypovolaemic shock. An almost normal long-term prognosis of aged patients after successful repair justifies even attempts of open repair, particularly in carefully selected patients.
Assuntos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ruptura Aórtica / Aneurisma da Aorta Abdominal Tipo de estudo: Etiology_studies / Prognostic_studies / Risk_factors_studies Limite: Aged / Aged80 / Female / Humans / Male Idioma: En Revista: Eur J Vasc Endovasc Surg Assunto da revista: ANGIOLOGIA Ano de publicação: 2011 Tipo de documento: Article País de afiliação: Suíça

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ruptura Aórtica / Aneurisma da Aorta Abdominal Tipo de estudo: Etiology_studies / Prognostic_studies / Risk_factors_studies Limite: Aged / Aged80 / Female / Humans / Male Idioma: En Revista: Eur J Vasc Endovasc Surg Assunto da revista: ANGIOLOGIA Ano de publicação: 2011 Tipo de documento: Article País de afiliação: Suíça