Kell hemolytic disease of the fetus. Combination treatment with plasmapheresis and intrauterine blood transfusion.
Transfus Apher Sci
; 45(1): 9-11, 2011 Aug.
Article
em En
| MEDLINE
| ID: mdl-21723196
ABSTRACT
We report the case of a 36-year old pregnant woman with a Kell alloimmunization (anti-K1), probably secondary to a previous blood transfusion, and a severe hemolytic disease of the fetus. Once the first fetal blood transfusion by cordocentesis was performed, we started treatment with repeated plasmapheresis to maintain anti-K1 titer below 132. With this scheme we did not need to perform a second intrauterine fetal blood transfusion and only mild anemia was found in the newborn. Taking into account that the rate of serious complications with plasmapheresis is lower than that related with intrauterine blood transfusion, this could be an alternative approach to repeated transfusions.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Transfusão de Sangue Intrauterina
/
Plasmaferese
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Doenças Fetais
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Doenças Hematológicas
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Anemia
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Sistema do Grupo Sanguíneo de Kell
Limite:
Adult
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Female
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Humans
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Pregnancy
Idioma:
En
Revista:
Transfus Apher Sci
Assunto da revista:
HEMATOLOGIA
Ano de publicação:
2011
Tipo de documento:
Article
País de afiliação:
Espanha