Enantioselective α-arylation of N-acyloxazolidinones with copper(II)-bisoxazoline catalysts and diaryliodonium salts.
J Am Chem Soc
; 133(35): 13778-81, 2011 Sep 07.
Article
em En
| MEDLINE
| ID: mdl-21848264
ABSTRACT
A new strategy for the catalytic enantioselective α-arylation of N-acyloxazolidinones with chiral copper(II)-bisoxazoline complexes and diaryliodonium salts is described. The mild catalytic conditions are operationally simple, produce valuable synthetic building blocks in excellent yields and enantioselectivities, and can be applied to the synthesis of important nonsteroidal anti-inflammatory agents and their analogues.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Oniocompostos
/
Sais
/
Compostos de Bifenilo
/
Cobre
/
Oxazolidinonas
/
Hidrocarbonetos Aromáticos
Idioma:
En
Revista:
J Am Chem Soc
Ano de publicação:
2011
Tipo de documento:
Article
País de afiliação:
Reino Unido