Immunotoxicity of 1-methyl-3-octylimidazolium bromide on brocarded carp (Cyprinus carpio L.).
Ecotoxicol Environ Saf
; 75(1): 180-6, 2012 Jan.
Article
em En
| MEDLINE
| ID: mdl-21944958
ABSTRACT
In the present study, the immunotoxicity of 1-methyl-3-octylimidazolium bromide ([C(8)mim]Br) on brocarded carp was evaluated by an acute exposure of 100-300mgL(-1) of [C(8)mim]Br for 7 days. The results showed 300mgL(-1) of [C(8)mim]Br exposure caused activity inhibition of specific and non-specific immune systems, mainly including IgM level, lysozyme activity, and complement C3 content, while 100mgL(-1) of [C(8)mim]Br activated fish immune system during the early periods of exposure (2-5 days). This result indicates that [C(8)mim]Br has immunotoxicity on brocarded carp. Additionally, histological observation revealed that 300mgL(-1) of [C(8)mim]Br-exposure led to remarkable damages to the hepatopancreas, kidney, and spleen of brocarded carp after 7 days of [C(8)mim]Br treatment, although not only change in kidney and spleen somatic indexes was found, but also no swelling or hemorrhage of carp viscera occurred.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Carpas
/
Imidazóis
/
Sistema Imunitário
Limite:
Animals
Idioma:
En
Revista:
Ecotoxicol Environ Saf
Ano de publicação:
2012
Tipo de documento:
Article
País de afiliação:
China