How the DNA damage response determines the fate of HTLV-1 Tax-expressing cells.
Retrovirology
; 9: 2, 2012 Jan 05.
Article
em En
| MEDLINE
| ID: mdl-22221708
ABSTRACT
How the Human T lymphotropic virus type 1 (HTLV-1) Tax protein stimulates proliferation while triggering cell cycle arrest and senescence remains puzzling. There is also a debate about the ability of Tax to activate or inhibit the DNA damage response. Here, we comment on these different activities and propose a conceptual rationale for the apparently conflicting observations.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Dano ao DNA
/
Vírus Linfotrópico T Tipo 1 Humano
/
Produtos do Gene tax
/
Reparo do DNA
Limite:
Humans
Idioma:
En
Revista:
Retrovirology
Assunto da revista:
VIROLOGIA
Ano de publicação:
2012
Tipo de documento:
Article
País de afiliação:
Bélgica