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[A woman in her 60s with multifactorial anaemia]. / En kvinne i 60-årene med kombinert anemi.
Frigstad, Svein-Oskar; Jønsson, Viggo; Moum, Bjørn.
Afiliação
  • Frigstad SO; Medisinsk avdeling, Oslo universitetssykehus, Norway. svein.oskar.frigstad@vestreviken.no
Tidsskr Nor Laegeforen ; 132(8): 965-8, 2012 Apr 30.
Article em Nor | MEDLINE | ID: mdl-22562330
Anaemia may be multifactorial in origin. We present a woman with autoimmune hepatitis and secondary warm autoimmune haemolytic anaemia and most likely also concomitant anaemia of chronic disease. A relapse of autoimmune haemolysis was successfully treated with steroids and high-dose intravenous immunoglobulin. At the same time, bleeding from angiodysplasia in the coecum was masked by unauthorised perorally administrated iron. No other cause of bleeding was found. During that period, she required extensive blood transfusions, up to several times per month. Surgical or endoscopic treatment of the bleeding angiodysplasia was not possible. Alloimmunisation developed as a complication to the large number of transfusions, despite the use of steroids. Treatment with somatostatin analogue markedly reduced the need of our patient for blood transfusions for a follow-up period of more than one year, and she has not experienced any side effects. We do not know how long the haemostasis achieved will last, however, we believe that this treatment may be an alternative for other patients as bleeding from angiodysplasia is not uncommon and is often difficult to eradicate.
Assuntos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Angiodisplasia / Hepatite Autoimune / Hemorragia Gastrointestinal / Anemia Hemolítica Autoimune Tipo de estudo: Diagnostic_studies / Etiology_studies Limite: Female / Humans / Middle aged Idioma: Nor Revista: Tidsskr Nor Laegeforen Ano de publicação: 2012 Tipo de documento: Article País de afiliação: Noruega

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Angiodisplasia / Hepatite Autoimune / Hemorragia Gastrointestinal / Anemia Hemolítica Autoimune Tipo de estudo: Diagnostic_studies / Etiology_studies Limite: Female / Humans / Middle aged Idioma: Nor Revista: Tidsskr Nor Laegeforen Ano de publicação: 2012 Tipo de documento: Article País de afiliação: Noruega