[A woman in her 60s with multifactorial anaemia]. / En kvinne i 60-årene med kombinert anemi.
Tidsskr Nor Laegeforen
; 132(8): 965-8, 2012 Apr 30.
Article
em Nor
| MEDLINE
| ID: mdl-22562330
Anaemia may be multifactorial in origin. We present a woman with autoimmune hepatitis and secondary warm autoimmune haemolytic anaemia and most likely also concomitant anaemia of chronic disease. A relapse of autoimmune haemolysis was successfully treated with steroids and high-dose intravenous immunoglobulin. At the same time, bleeding from angiodysplasia in the coecum was masked by unauthorised perorally administrated iron. No other cause of bleeding was found. During that period, she required extensive blood transfusions, up to several times per month. Surgical or endoscopic treatment of the bleeding angiodysplasia was not possible. Alloimmunisation developed as a complication to the large number of transfusions, despite the use of steroids. Treatment with somatostatin analogue markedly reduced the need of our patient for blood transfusions for a follow-up period of more than one year, and she has not experienced any side effects. We do not know how long the haemostasis achieved will last, however, we believe that this treatment may be an alternative for other patients as bleeding from angiodysplasia is not uncommon and is often difficult to eradicate.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Angiodisplasia
/
Hepatite Autoimune
/
Hemorragia Gastrointestinal
/
Anemia Hemolítica Autoimune
Tipo de estudo:
Diagnostic_studies
/
Etiology_studies
Limite:
Female
/
Humans
/
Middle aged
Idioma:
Nor
Revista:
Tidsskr Nor Laegeforen
Ano de publicação:
2012
Tipo de documento:
Article
País de afiliação:
Noruega