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Existence of serotonin and neuropeptides-immunoreactive endocrine cells in the small and large intestines of the mole-rats (Spalax leucodon).
Yaman, M; Bayrakdar, A; Tarakçi, B G.
Afiliação
  • Yaman M; Department of Histology and Embryology, Faculty of Veterinary Medicine, Firat University, 23119 Elazig, Turkey. yaman@firat.edu.tr
Tissue Cell ; 44(4): 257-63, 2012 Aug.
Article em En | MEDLINE | ID: mdl-22608308
The present study was conducted to clarify the regional distribution and relative frequency of endocrine cells secreting serotonin, substance P (SP), cholecystokinin-8 (CCK-8), vasoactive intestinal polypeptide (VIP) and neurotensin in the small and large intestine of the mole-rats (Spalax leucodon), by specific immunohistochemical methods. In the small and large intestine of mole-rats (Spalax leucodon), serotonin, SP and VIP were identified with various frequencies, but CCK-8 and neurotensin were not observed. Most of the IR cells in the small and large intestine were located in the intestinal crypt and epithelium however, they were more frequency in the intestinal crypt. Serotonin-IR cells were detected throughout the whole intestinal tract, predominantly in the duodenum and colon. SP-IR cells were demonstrated throughout the whole intestinal tract except for the ileum and rectum with highest frequencies in the cecum. VIP-IR cells were found in all parts of the small intestine except for the large intestine. In conclusion, the general distribution patterns and relative frequency of intestinal endocrine cells of the mole-rats (Spalax leucodon) was similar to those of some rodent species. However, some species-dependent unique distributions and frequencies characteristics of endocrine cells were also observed in the present study.
Assuntos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neuropeptídeos / Serotonina / Células Enteroendócrinas / Ratos-Toupeira / Intestino Grosso / Intestino Delgado Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Tissue Cell Ano de publicação: 2012 Tipo de documento: Article País de afiliação: Turquia

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neuropeptídeos / Serotonina / Células Enteroendócrinas / Ratos-Toupeira / Intestino Grosso / Intestino Delgado Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Tissue Cell Ano de publicação: 2012 Tipo de documento: Article País de afiliação: Turquia