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A Laplace pressure based microfluidic trap for passive droplet trapping and controlled release.
Simon, Melinda G; Lin, Robert; Fisher, Jeffrey S; Lee, Abraham P.
Afiliação
  • Simon MG; Department of Biomedical Engineering, University of California, Irvine, 3201 Natural Sciences II, Irvine, California 92697, USA.
Biomicrofluidics ; 6(1): 14110-1411013, 2012 Mar.
Article em En | MEDLINE | ID: mdl-22662095
Here, we present a microfluidic droplet trap that takes advantage of the net Laplace pressure force generated when a droplet is differentially constricted. Mathematical simulations were first used to understand the working range of the component; followed by finite element modeling using the CFD software package to further characterize the behavior of the system. Controlled release of the trapped droplets is also demonstrated through both a mechanical method and a chemical method that manipulates the total pressure exerted on the trapped droplet. The unique design of this trapping device also provides the capability for selection of a single droplet from a train, as well as droplet fusion.

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Biomicrofluidics Ano de publicação: 2012 Tipo de documento: Article País de afiliação: Estados Unidos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Biomicrofluidics Ano de publicação: 2012 Tipo de documento: Article País de afiliação: Estados Unidos