[Sirtuin1 and lung disease].
Yao Xue Xue Bao
; 47(4): 417-20, 2012 Apr.
Article
em Zh
| MEDLINE
| ID: mdl-22799020
ABSTRACT
Sirtuin1 (Sirt1) is a NAD-dependent class III histone deacetylase (HDAC), and regulates pulmonary immune/inflammatory system and the aging process mainly through post-translational modification. Sirt1 could become a potential target for treatment of lung diseases due to participating in the development of a variety of lung diseases. In this paper, physiological characteristics, biological activities, modification regulations and its relationship with chronic obstructive pulmonary emphysema, asthma and lung cancer are reviewed.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Sirtuína 1
/
Pneumopatias
Limite:
Animals
/
Humans
Idioma:
Zh
Revista:
Yao Xue Xue Bao
Ano de publicação:
2012
Tipo de documento:
Article
País de afiliação:
China