[Viscosity changes in thickened water due to the addition of highly prescribed drugs in geriatrics]. / Cambios en la viscosidad del agua con espesantes por la adición de fármacos altamente prescritos en geriatría.
Nutr Hosp
; 27(4): 1298-303, 2012.
Article
em Es
| MEDLINE
| ID: mdl-23165577
ABSTRACT
INTRODUCTION:
Dysphagia is a swallowing disorder with a high incidence in the geriatric patient related with an increased risk for undernutrition and pneumonia due to bronchial aspiration. In this condition, it is usual to add commercial thickeners in liquids, as well as the addition of drugs in this mixture to improve their administration. However, there are no studies regarding the possible change in viscosity produced by their addition.OBJECTIVES:
To assess the change in viscosity of water thickened with commercial products by adding the drugs frequently used in elderly patients.METHODS:
Samples of water mixed with the commercial thickener Resource (modified corn starch) or Nutilis (modified corn starch, maltodextrin, and gums tara, xhantan, and guar) to achieve an intermediate consistence as "honey". The viscosity of these samples was measured as well as for similar samples to which one of the following drugs was added galantamine, rivastigmin, ciprofloxacin, cholecalciferol, memantine, fosfomycin, calcium, and amoxicillin/clavulanic acid.RESULTS:
In the samples with Resource thickener we observed decreased viscosity by adding galantamine, memantine, fosfomycin or calcium, and increased viscosity with amoxicillin/clavulanic acid. The viscosity of the samples with Nutilis® decreased with galantamine, rivastigmine, amoxicillin/clavulanic acid, fosfomycin and calcium.CONCLUSION:
The viscosity of water with commercial thickeners may be affected by some drugs or their preservatives, which may influence the swallowing capability. It is recommended to perform further in vitro and in vivo studies in order to adjust these formulations if necessary.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Água
/
Administração Oral
/
Medicamentos sob Prescrição
Limite:
Aged
/
Female
/
Humans
/
Male
Idioma:
Es
Revista:
Nutr Hosp
Assunto da revista:
CIENCIAS DA NUTRICAO
Ano de publicação:
2012
Tipo de documento:
Article