Monoclonal origin of primary unilateral multifocal pleomorphic adenoma of the parotid gland.
Hum Pathol
; 44(5): 923-6, 2013 May.
Article
em En
| MEDLINE
| ID: mdl-23332926
ABSTRACT
Primary multiple pleomorphic adenomas in a unilateral parotid gland in previously untreated patients is a rare finding, and little is known about the etiology and pathogenesis. Here, a highly unusual case of a primary multifocal pleomorphic adenoma consisting of 15 individual nodules is presented. It is shown that all nodes are clonally related and thus share a common cell of origin excluding an independent multifocal pathogenesis. Most likely, multifocal pleomorphic adenoma represents parasitic nodules that have been detached from a main nodule, which may have been the result of undisclosed trauma.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Neoplasias Parotídeas
/
Adenoma Pleomorfo
/
Neoplasias Primárias Múltiplas
Limite:
Female
/
Humans
/
Middle aged
Idioma:
En
Revista:
Hum Pathol
Assunto da revista:
PATOLOGIA
Ano de publicação:
2013
Tipo de documento:
Article
País de afiliação:
Holanda