Familial LCAT deficiency in a child with nephrotic syndrome.
Clin Nephrol
; 82(3): 211-4, 2014 Sep.
Article
em En
| MEDLINE
| ID: mdl-23391322
ABSTRACT
BACKGROUND:
Lecitin cholesterol acyltransferase (LCAT) deficiency comprises a group of rare disorders related to HDL metabolism. These disorders are characterized by ophthalmologic, hematologic, and renal findings. Case diagnosis/treatment A 15-year-old female who presented with nephrotic syndrome and hypertension was diagnosed with LCAT deficiency by renal biopsy and LCAT enzyme activity. Her edema and hypertension improved with diuretic and antihypertensive therapies. Continued care of her LCAT deficiency is ongoing.CONCLUSION:
Although rare, LCAT deficiency should be in the differential diagnosis of nephrotic syndrome in the setting of abnormally low HDL cholesterol levels.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Deficiência da Lecitina Colesterol Aciltransferase
/
Síndrome Nefrótica
Tipo de estudo:
Diagnostic_studies
/
Etiology_studies
Limite:
Adolescent
/
Female
/
Humans
Idioma:
En
Revista:
Clin Nephrol
Ano de publicação:
2014
Tipo de documento:
Article