Biology of the staphylococcal conjugative multiresistance plasmid pSK41.
Plasmid
; 70(1): 42-51, 2013 Jul.
Article
em En
| MEDLINE
| ID: mdl-23415796
ABSTRACT
Plasmid pSK41 is a large, low-copy-number, conjugative plasmid from Staphylococcus aureus that is representative of a family of staphylococcal plasmids that confer multiple resistances to a wide range of antimicrobial agents. The plasmid consists of a conserved plasmid backbone containing the genes for plasmid housekeeping functions, which is punctuated by copies of IS257 that flank a Tn4001-hybrid structure and cointegrated plasmids that harbour resistance genes. This review summarises the current understanding of the biology of pSK41, focussing on the systems responsible for its replication, maintenance and transmission, and their regulation.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Plasmídeos
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Staphylococcus aureus
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DNA Bacteriano
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Regulação Bacteriana da Expressão Gênica
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Conjugação Genética
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Farmacorresistência Bacteriana Múltipla
Idioma:
En
Revista:
Plasmid
Ano de publicação:
2013
Tipo de documento:
Article
País de afiliação:
Austrália