[Study on prescription of self-microemulsifying drug delivery system of mangiferin phospholipid complex].
Zhong Yao Cai
; 35(9): 1508-11, 2012 Sep.
Article
em Zh
| MEDLINE
| ID: mdl-23451508
ABSTRACT
OBJECTIVE:
To study formulation of self-microemulsifying drug delivery system (SMEDDS) of mangiferin phospholipid complex and improve dissolution and bioavailability of mangiferin.METHODS:
Ternary phase diagram was applied to optimize the prescription of self-microemulsifying drug delivery system of mangiferin phospholipid complex, and the best recipe was selected by comprehensive evaluation of the speed of microemulsifying, microemulsion size and electric potential.RESULTS:
The optimum formulation of SMEDDS was composed of IPM-Cremphor EL35-labrasol = 2 4.8 3.2.CONCLUSION:
Self-microemulsifying drug delivery system of mangiferin phospholipid complex can effectively improve the dissolution of Mangiferin.
Buscar no Google
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Fosfolipídeos
/
Sistemas de Liberação de Medicamentos
/
Xantonas
/
Emulsões
Idioma:
Zh
Revista:
Zhong Yao Cai
Assunto da revista:
TERAPIAS COMPLEMENTARES
Ano de publicação:
2012
Tipo de documento:
Article
País de afiliação:
China