Anestesia/efeitos adversos; Tauopatias/etiologia; Humanos

3-repeat tau isoforms; 3R; 3×Tg-AD; 4-repeat tau isoforms; 4R; AD; AKT/PKB; APP; Alzheimer's disease; Anesthesia; Aß; BDNF; CSF; CaMKII; Dex; ERK; GABA; GSK-3ß; JNK; Kinase; MAC; MAPK; MT; MWM; Morris water maze; N-methyl d-aspartate receptor; NFT; NMDA-R; NR2B; PP1; PP2A; PP2B; PS-1; Phosphatase; Ser; Src; Tau; Tau-SH-SY5Y cells; Thr; amyloid-ß; amyloid-ß precursor protein; brain-derived neurotrophic factor; c-Jun N-terminal kinase; calcium/calmodulin-dependent protein kinase II; cdk5; cerebrospinal fluid; cyclin-dependent kinase 5; dexmedetomidine; extracellular signal-regulated kinase; glycogen synthase kinase-3ß; human neuroblastoma cells constitutively expressing human tau with 3 microtubule-binding domains; i.p.; intra peritoneal; microtubule; minimum alveolar concentration; mitogen-activated protein kinase; neurofibrillary tangles; presenilin-1; protein kinase B; protein phosphatase 1; protein phosphatase 2A; protein phosphatase 2B; serine; short for sarcoma, a non-receptor tyrosine kinase; subunit 2B of NMDA receptor; threonine; triple transgenic Alzheimer's disease mouse model; γ-aminobutyric acid