The generation and inhibition of hedonically-driven food intake: behavioral and neurophysiological determinants in healthy weight individuals.
Physiol Behav
; 121: 25-34, 2013 Sep 10.
Article
em En
| MEDLINE
| ID: mdl-23562869
ABSTRACT
Given the progressive weight gain of populations in numerous countries, it can be presumed that many people eat beyond the point of nutritional repletion, in other words, for hedonic rather than homeostatic reasons. This kind of overeating is hypothesized to be due to a combination of obesogenic food environments, hyperresponsivity to food reward and deficits in inhibiting pleasure-based food intake. This paper explores the interrelationship of the latter two constructs and their neurobiological underpinnings. It also examines the potential brain changes that may take place during the course of repeated hedonic overeating and weight gain. It is hypothesized that fronto-striatal circuitry plays a primary role in this process, and that, over time, inhibitory control is eroded as reward responsiveness to highly palatable food cues increases. The unique neurobiological profile of normal weight but at-risk individuals may perpetuate continued weight gain; the neurobehavioral consequences of overeating and weight may make the permanent reversal of such weight gain infeasible.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Recompensa
/
Aumento de Peso
/
Ingestão de Alimentos
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Comportamento Alimentar
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Inibição Psicológica
Limite:
Humans
Idioma:
En
Revista:
Physiol Behav
Ano de publicação:
2013
Tipo de documento:
Article