[Tree shrews under the spot light: emerging model of human diseases].
Dongwuxue Yanjiu
; 34(2): 59-69, 2013 Apr.
Article
em Zh
| MEDLINE
| ID: mdl-23572354
ABSTRACT
Animal models are indispensible in biomedical research and have made tremendous contributions to answer fundamental questions on human biology, disease mechanisms, and to the development of new drugs and diagnostic tools. Due to the limitations of rodent models in translational medicine, tree shrews (Tupaia belangeri chinensis), the closest relative of primates, have attracted increasing attention in modeling human diseases and therapeutic responses. Here we discuss the recent progress in tree shrew biology and the development of tree shrews as human disease models including infectious diseases, metabolic diseases, neurological and psychiatric diseases, and cancers. Meanwhile, the current problems and future perspectives of the tree shrew model are explored.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Tupaiidae
/
Modelos Animais de Doenças
Limite:
Animals
/
Humans
Idioma:
Zh
Revista:
Dongwuxue Yanjiu
Ano de publicação:
2013
Tipo de documento:
Article
País de afiliação:
China